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Page 9 of 19

  1. Convection-enhanced delivery (CED), a direct method for drug delivery to the brain through intraparenchymal microcatheters, is a promising strategy for intracerebral pharmacological therapy. By establishing a ...

    Authors: Neil U Barua, Alison S Bienemann, Shirley Hesketh, Marcella J Wyatt, Emma Castrique, Seth Love and Steven S Gill

    Citation: Fluids and Barriers of the CNS 2012 9:2

    Content type: Research

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  2. The cerebrospinal fluid (CSF) tap test (TT) has been regarded as an important test for the prediction of shunt effectiveness in patients with suspected idiopathic normal pressure hydrocephalus (iNPH). Although...

    Authors: Masatsune Ishikawa, Masaaki Hashimoto, Etsuro Mori, Nobumasa Kuwana and Hiroaki Kazui

    Citation: Fluids and Barriers of the CNS 2012 9:1

    Content type: Research

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  3. This review examines the use of transporter knockout (KO) animals to evaluate transporter function at the choroid plexus (the blood-CSF barrier; BCSFB). Compared to the blood-brain barrier, there have been few...

    Authors: Richard F Keep and David E Smith

    Citation: Fluids and Barriers of the CNS 2011 8:26

    Content type: Review

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  4. Elevated plasma fibrinogen levels are a well known finding in acute infectious diseases, acute stroke and myocardial infarction. However its role in the cerebrospinal fluid (CSF) of acute and chronic central (...

    Authors: Rainer Ehling, Franziska Di Pauli, Peter Lackner, Bettina Kuenz, Wolfram Santner, Andreas Lutterotti, Claudia Gneiss, Harald Hegen, Michael Schocke, Florian Deisenhammer, Thomas Berger and Markus Reindl

    Citation: Fluids and Barriers of the CNS 2011 8:25

    Content type: Short paper

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  5. Peripheral administration of lipopolysaccharide (LPS) induces inflammation and increases cerebral prostaglandin E2 (PGE2) concentration. PGE2 is eliminated from brain across the blood-brain barrier (BBB) in mice,...

    Authors: Shin-ichi Akanuma, Yasuo Uchida, Sumio Ohtsuki, Masanori Tachikawa, Tetsuya Terasaki and Ken-ichi Hosoya

    Citation: Fluids and Barriers of the CNS 2011 8:24

    Content type: Research

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  6. AhR activates the transcription of several target genes including CYP1B1. Recently, we showed CYP1B1 as the major cytochrome P450 (CYP) enzyme expressed in human brain microvessels. Here, we studied the effect of...

    Authors: Aude Jacob, Anika MS Hartz, Sophie Potin, Xavier Coumoul, Salah Yousif, Jean-Michel Scherrmann, Björn Bauer and Xavier Declèves

    Citation: Fluids and Barriers of the CNS 2011 8:23

    Content type: Research

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  7. Hydrocephalus is associated with enlargement of cerebral ventricles. We hypothesized that magnetic resonance (MR) imaging parameters known to be influenced by tissue water content would change in parallel with...

    Authors: Marc R Del Bigio, Ili Slobodian, Angela E Schellenberg, Richard J Buist and Tanya L Kemp-Buors

    Citation: Fluids and Barriers of the CNS 2011 8:22

    Content type: Research

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  8. Age is the major risk factor for many neurodegenerative diseases, including Alzheimer's disease (AD). There is an accumulation of amyloid-beta peptides (Aβ) in both the AD brain and the normal aging brain. Cle...

    Authors: Crissey L Pascale, Miles C Miller, Catherine Chiu, Matthew Boylan, Ilias N Caralopoulos, Liliana Gonzalez, Conrad E Johanson and Gerald D Silverberg

    Citation: Fluids and Barriers of the CNS 2011 8:21

    Content type: Research

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  9. Cerebrovascular dysfunction has been considered to cause impairment of cerebral amyloid-β peptide (Aβ) clearance across the blood-brain barrier (BBB). Further, low levels of vitamin D are associated with incre...

    Authors: Shingo Ito, Sumio Ohtsuki, Yasuko Nezu, Yusuke Koitabashi, Sho Murata and Tetsuya Terasaki

    Citation: Fluids and Barriers of the CNS 2011 8:20

    Content type: Research

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  10. The mechanisms behind formation and filling of intracranial arachnoid cysts (AC) are poorly understood. The aim of this study was to evaluate AC fluid by proteomics to gain further knowledge about ACs. Two goa...

    Authors: Magnus Berle, Ann C Kroksveen, Øystein A Haaland, Thin T Aye, Jill A Opsahl, Eystein Oveland, Knut Wester, Rune J Ulvik, Christian A Helland and Frode S Berven

    Citation: Fluids and Barriers of the CNS 2011 8:19

    Content type: Research

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  11. Neuropeptides may have considerable potential in the treatment of acute and chronic neurological diseases. Encapsulated genetically engineered cells have been suggested as a means for sustained local delivery ...

    Authors: Silke Glage, Petra M Klinge, Miles C Miller, Christine Wallrapp, Peter Geigle, Hans J Hedrich and Thomas Brinker

    Citation: Fluids and Barriers of the CNS 2011 8:18

    Content type: Research

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  12. Guanidino compounds (GCs), such as creatine, phosphocreatine, guanidinoacetic acid, creatinine, methylguanidine, guanidinosuccinic acid, γ-guanidinobutyric acid, β-guanidinopropionic acid, guanidinoethane sulf...

    Authors: Masanori Tachikawa and Ken-ichi Hosoya

    Citation: Fluids and Barriers of the CNS 2011 8:13

    Content type: Review

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  13. Phase-contrast magnetic resonance imaging (PC-MRI) enables quantification of cerebrospinal fluid (CSF) flow and total cerebral blood (tCBF) flow and may be of value for the etiological diagnosis of neurodegene...

    Authors: Soraya El Sankari, Catherine Gondry-Jouet, Anthony Fichten, Olivier Godefroy, Jean Marie Serot, Hervé Deramond, Marc Etienne Meyer and Olivier Balédent

    Citation: Fluids and Barriers of the CNS 2011 8:12

    Content type: Research

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  14. In patients with idiopathic normal pressure hydrocephalus (iNPH) responding to shunt surgery, we have consistently found elevated intracranial pressure (ICP) wave amplitudes during diagnostic ICP monitoring pr...

    Authors: Per K Eide

    Citation: Fluids and Barriers of the CNS 2011 8:11

    Content type: Research

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  15. Although the gene expression profile of several tissues in humans and in rodent animal models has been explored, analysis of the complete choroid plexus (CP) transcriptome is still lacking. A better characteri...

    Authors: Fernanda Marques, João C Sousa, Giovanni Coppola, Fuying Gao, Renato Puga, Helena Brentani, Daniel H Geschwind, Nuno Sousa, Margarida Correia-Neves and Joana A Palha

    Citation: Fluids and Barriers of the CNS 2011 8:10

    Content type: Research

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  16. The French scientist Charles Benjamin Rouget identified the pericyte nearly 140 years ago. Since that time the role of the pericyte in vascular function has been difficult to elucidate. It was not until the de...

    Authors: Drew Bonkowski, Vladimir Katyshev, Roumen D Balabanov, Andre Borisov and Paula Dore-Duffy

    Citation: Fluids and Barriers of the CNS 2011 8:8

    Content type: Review

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  17. The human brain has no lymphatic system, but produces over a half-liter each day of cerebrospinal fluid. The cerebrospinal fluid is secreted at the choroid plexus and occupies the cavities of the four ventricl...

    Authors: William M Pardridge

    Citation: Fluids and Barriers of the CNS 2011 8:7

    Content type: Commentary

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  18. The content and composition of cerebrospinal fluid (CSF) is determined in large part by the choroid plexus (CP) and specifically, a specialized epithelial cell (CPe) layer that responds to, synthesizes, and tr...

    Authors: Ana Maria Gonzalez, Sonia Podvin, Shuh-Yow Lin, Miles C Miller, Hannah Botfield, Wendy E Leadbeater, Andrew Roberton, Xitong Dang, Stuart E Knowling, Elena Cardenas-Galindo, John E Donahue, Edward G Stopa, Conrad E Johanson, Raul Coimbra, Brian P Eliceiri and Andrew Baird

    Citation: Fluids and Barriers of the CNS 2011 8:6

    Content type: Research

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  19. Neuronal activity within the central nervous system (CNS) strictly depends on homeostasis and therefore does not tolerate uncontrolled entry of blood components. It has been generally believed that under norma...

    Authors: Britta Engelhardt and Caroline Coisne

    Citation: Fluids and Barriers of the CNS 2011 8:4

    Content type: Review

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  20. Tracing the exact origins of modern science can be a difficult but rewarding pursuit. It is possible for the astute reader to follow the background of any subject through the many important surviving texts fro...

    Authors: Shane A Liddelow

    Citation: Fluids and Barriers of the CNS 2011 8:2

    Content type: Review

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  21. Authors: Montserrat Guerra, Deborah Sival, Antonio Jimenez, María Dolores Dominguez Pinos, Wilfred den Dunnen, Luis Federico Bátiz, José Manuel Pérez-Figares and Esteban Rodríguez

    Citation: Cerebrospinal Fluid Research 2010 7(Suppl 1):S56

    Content type: Poster presentation

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    This article is part of a Supplement: Volume 7 Supplement 1

  22. Authors: Agustin Castañeyra-Perdomo, Ibrahim Gonzalez-Marrero, Rafael Castro, Agustin Castañeyra-Ruiz, Hector de Paz-Camona, Leandro Castañeyra-Ruiz, Juan M Gonzalez-Toledo and Emilia M Carmona-Calero

    Citation: Cerebrospinal Fluid Research 2010 7(Suppl 1):S29

    Content type: Oral presentation

    Published on:

    This article is part of a Supplement: Volume 7 Supplement 1