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Aims and scope

Fluids and Barriers of the CNS is an open access, peer-reviewed, online journal that considers manuscripts on all CNS fluids and barrier systems in health and disease.

Fluids and Barriers of the CNS is affiliated to the International Brain Barriers Society (IBBS) and the International Society for Hydrocephalus and CSF Disorders (ISHCSF). 


Article collections

Thematic Series
Genetic disorders and genetic manipulation at the blood-brain barriers
Fluids and Barriers of the CNS

Thematic Series
Advances in in vitro modeling of the blood-brain barrier and neurovascular unit
Fluids and Barriers of the CNS

Thematic series
CNS Fluid and Solute Movement: Physiology, Modelling and Imaging
Fluids and Barriers of the CNS

Thematic series
Brain barriers and their microenvironment: Emerging models and techniques
Edited by Danica Stanimirovic, Britta Engelhardt, Elizabeth de Lange

View all article collections

Latest supplements

Abstracts from the International Symposium 2022 -  Signal Transduction at the Blood-Brain Barriers

Volume 20 Supplement 1
Meeting abstracts
Bari, Italy. 21-23 September 2022

Abstracts from Hydrocephalus 2022 - The Fourteenth Meeting of the Hydrocephalus Society

Volume 19 Supplement 1
Meeting abstracts
Gothenburg, Sweden. 9-12 September 2022

View all supplements

About the Editors

Lester R Drewes, Editor-in-Chief

Lester Drewes is currently Professor  of Biochemistry and Molecular Biology at the University of Minnesota Duluth Medical School, and past President of the International Brain Barriers Society. Read more

M Hamilton PicMark G Hamilton, Editor-in-Chief

Mark G Hamilton, MDCM, FRCSC, FAANS, is from the University of Calgary, Cumming School of Medicine, Department of Clinical Neurosciences, Division of Neurosurgery. Read More.

Hazel C Jones, Founding Editor

Hazel Jones is Visiting Senior Research Fellow, Institute of Pharmaceutical Sciences, King's College London and lately Courtesy Research Professor, Department of Pharmacology and Therapeutics, University of Florida. Read more

Richard F Keep, Editor-in-Chief

Richard Keep is currently Professor in the Department of Neurosurgery and in the Department of Molecular and Integrative Physiology at the University of Michigan. He is also Director of the Crosby Neurosurgical Laboratories and Associate Chair for Research in Neurosurgery. Read more

Retirement of Dr. Hazel Jones as Co-Editor-in-Chief of Fluids and Barriers of the CNS. Dr. Mark Hamilton becomes Co-Editor-in-Chief.

Dr. Hazel Jones is retiring as Co-Editor-in-Chief of Fluids and Barriers of the CNS (as of May 1st, 2023).  We are happy to announce that Dr. Mark Hamilton (University of Calgary) will become Co-Editor-in-Chief (joining Drs. Richard Keep and Lester Drewes). Dr. Hamilton, a neurosurgeon, is an internationally recognized expert on hydrocephalus and Past President of the Hydrocephalus Society (ISHCSF). He will have a particular role in overseeing submissions related to hydrocephalus and CNS fluids, as well as guiding the future of the journal. Dr. Hamilton is warmly welcomed as he assumes his new role.

See here for full announcement.


Lester R Drewes, University of Minnesota, USA
Mark Hamilton, University of Calgary, Canada
Richard F Keep, University of Michigan, USA

Society affiliations

International Brain Barriers Society (IBBS)

New Content ItemFluids and Barriers of the CNS is an official journal of the IBBS: a scientific and educational non-profit organisation advocating scientific and clinical research on the biological barriers in the central nervous system.

The Hydrocephalus Society

Fluids and Barriers of the CNS is an official journal of the Hydrocephalus Society: a non-profit organization that aims to advance the art and science of clinical care and research into hydrocephalus and CSF disorders, and promote the best possible care for patients.

All IBBS and ISHCSF members are eligible for a 15% discount when publishing with Fluids and Barriers of the CNS.

Read more

In memoriam - Dr. David Begley

Dr_David_BegleyIt is with much sadness that we mark the recent passing of FBCN Editorial Board Member Dr. David Begley, a highly valued member of our field. Please read more here

Journal News

We are pleased to announce that the official 2-year impact factor of FBCNS for 2022 is now 7.3, with a ranking of 33 and in the 88th percentile among Neuroscience journals.

New Thematic Series - Open

Genetic Aspects of Hydrocephalus
This series addresses new research and reviews on genetic aspects of hydrocephalus, including both human genetic studies seeking to identify new genetic causes of hydrocephalus and animal studies using genetic manipulations to provide insight into the role of specific proteins/pathways in regulating CSF dynamics and hydrocephalus development. Studies on the role of epigenetics in hydrocephalus are also most welcome.

Latest Review

Occludin: a gatekeeper of brain Infection by HIV-1. Compromised structure and function of the blood-brain barrier (BBB) is one of the pathological hallmarks of brain infection by HIV-1... 
Authors: Silvia Torices, Leah Daire, Sierra Simon, Oandy Naranjo, Luisa Mendoza, Timea Teglas, Nikolai Fattakhov, Daniel Adesse and Michal Toborek 
Citation: Fluids and Barriers of the CNS 2023 20:73 
Published on: 16 October 2023

Featured Article

Proteomic interrogation of the meninges reveals the molecular identities of structural components and regional distinctions along the CNS axis
The meninges surround the brain and spinal cord, affording physical protection while also serving as a niche of neuroimmune activity...
Authors: Elise Santorella, Jeremy L. Balsbaugh, Shujun Ge, Parisa Saboori, David Baker and Joel S. Pachter
Citation: Fluids and Barriers of the CNS 2023 20:74
Published on: 19 October 2023

Scimago journal rank

FBCNS is ranked in the top quartile of the Developmental Neuroscience, Neurology and Neuroscience subject categories, by SCImago Journal Rank.

2022 Best Presentation Winners - Hydrocephalus 2022 Conference

We are pleased to announce the winners of the awards for best presentations sponsored by the International Society for Hydrocephalus and CSF Disorders and by Fluids and Barriers of the CNS at this year’s Hydrocephalus conference, September 9-12, Gothenburg Sweden.

Find out more about the winners here.

2023 Young Investigator Awards – Cerebrovascular Biology 2023

We are pleased to announce the winners of the awards for best abstracts/posters sponsored by Fluids and Barriers of the CNS and the International Brain Barriers Society at CVB-2023 in Uppsala, Sweden, on June 18-22, 2023.

Find out more about the winners here.

Forthcoming Conferences

Lund Glymphatic Symposium, June 17-20, 2024 in Lund, Sweden.
The inaugural Lund Glymphatic Symposium brings together the world leading researchers on brain clearance, neurofluids and the glymphatic system. The organizing committee consists of Dr. Iben Lundgaard, Tekla Kylkilahti, and Denys Kovalenko. The program, speakers, abstract submissions, and accommodation information are available on the website.

2nd Belgian Brain Barriers Symposium, KU Leuven, Leuven, Belgium, November 13, 2023,

Barriers of the CNS, Gordon Research Conference, Genetics to Physiology and Bench to Bedside, June 9- 14, 2024, Colby-Sawyer College, NH, USA.

Society for Research into Hydrocephalus and Spina Bifida, Annual meeting June 26-29, 2024, Liverpool, UK.

16th Meeting of the Hydrocephalus Society (International Society for Hydrocephalus and CSF Disorders). Hydrocephalus 2024, Nagoya, Japan, September 13-16, 2024.

15th International conference on Cerebral Vascular Biology, Ann Arbor, USA, June 22-255, 2025,

Annual Journal Metrics

  • 2022 Citation Impact
    7.3 - 2-year Impact Factor
    7.5 - 5-year Impact Factor
    1.772 - SNIP (Source Normalized Impact per Paper)
    1.657 - SJR (SCImago Journal Rank)

    2022 Speed
    7 days submission to first editorial decision for all manuscripts (Median)
    97 days submission to accept (Median)

    2022 Usage 
    1,007 Altmetric mentions