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Fig. 9 | Fluids and Barriers of the CNS

Fig. 9

From: Diagnostic biomarker kinetics: how brain-derived biomarkers distribute through the human body, and how this affects their diagnostic significance: the case of S100B

Fig. 9

A Effects of removing kidney filtration from the model. Note the increase in muscle S100B and venous levels, showing that glomerular filtration rate controls peripheral levels and kinetic behavior of S100B. B Effect of varying glomerular filtration on S100B. Note the drop of venous S100B with increased glomerular filtration rate and the lack of effect of GFR on brain interstitial levels and gut S100B. Also note organ-dependent changes in S100B with low or high GFR

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Fluids and Barriers of the CNS

ISSN: 2045-8118