Fig. 2
Structure of a single organ in Model 1. Note that two equilibria reactions (Kr and Kf) describe the passage of biomarkers from the organ’s parenchyma (interstitial space) to blood and vice versa. A lymphatic vessel is also depicted. Qorg and Lorg refer to the blood flow into and out of the organ, and lymphatic flow, respectively. The values of Q for each organ are listed in Table 1