Table 1 Advantages and disadvantages of microdialysis and microperfusion
From: Microdialysis and microperfusion electrodes in neurologic disease monitoring
| Microdialysis | Microperfusion | |
|---|---|---|
| Advantages |
Strong literature foundation Able to target specific molecular weights Single pump configuration |
Less well characterized Largely avoids biofouling Collects biomarkers of all sizes Simple probe construction Simple sterilization process |
| Disadvantages |
Membrane biofouling Complicated probe construction Lack of commercial membrane sizes Membrane expense Membrane sterilization challenges |
Tissue damage at high flow rates Secondary pull pump required |