Table 1 Advantages and disadvantages of microdialysis and microperfusion
From: Microdialysis and microperfusion electrodes in neurologic disease monitoring
| Â | Microdialysis | Microperfusion |
|---|---|---|
Advantages | Strong literature foundation Able to target specific molecular weights Single pump configuration | Less well characterized Largely avoids biofouling Collects biomarkers of all sizes Simple probe construction Simple sterilization process |
Disadvantages | Membrane biofouling Complicated probe construction Lack of commercial membrane sizes Membrane expense Membrane sterilization challenges | Tissue damage at high flow rates Secondary pull pump required |