Active induction of experimental autoimmune encephalomyelitis by MOG35-55 peptide immunization is associated with differential responses in separate compartments of the choroid plexus

Table 1 Genes similarly up-regulated in CP stromal capillary tissue from both MOG-CFA/PTX- and CFA-PTX-immunized mice at day 9 p.i

Genes modulated similarly in stromal CP capillary of MOG-CFA/PTX mice at day 9 p.i
Gene name	Gene name
B2m^‡	ll15*
Bcl2l1	ll18*
C3**^‡	ll1b**
Ccl19^‡	ll7
Ccl2**	Lrp2
Ccl5**^‡	Nfkb1*
Ccr2**	Nfkb2
Cd34**	Ptgs*^‡
Cd80	Sele**
Cd86*	Selp**
Cd8a	Amad3^‡
Col4a5	Socs2
Csf1*	Stat1**
Cxcl10**	Stat3
Cxcr3*	Stat4^‡
Ece1	Stat6
Edn1	Tbx21
Fas	Tfrc*
Fn1	Tgfb1
Gzmb^‡	Cd40
Hmox1	Fasl**
Hprt1	Vcam1
lcos	Vegfa
lfng**

genes with * ≥ 5 and ** ≥ 10 fold increase in expression in comparison to Naïve animals.
Relative mRNA expression values of 93 immune-related genes were determined by immuno-LCM/TLDA in CP stromal capillary tissue from immunized and naïve mice at day 9 p.i. At this early time-point, all 49 immunization-induced genes were similarly stimulated in both MOG-CFA/PTX- and CFA-PTX-immunized mice compared to naïve animals, and only these are listed. ^‡ denotes genes that show specific upregulation later on with disease progression on day 15.

ISSN: 2045-8118