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Fig. 8 | Fluids and Barriers of the CNS

Fig. 8

From: SARS-CoV-2 causes dysfunction in human iPSC-derived brain microvascular endothelial cells potentially by modulating the Wnt signaling pathway

Fig. 8

BMEC inflammation by SARS-CoV-2 examined after CHIR99021 treatment. A Cells were treated with CHIR99021 (3 μM) 1 h before SARS-CoV-2 infection (MOI = 1). Inflammatory response genes (CCL3, CCL5, CXCL2, CXCL3, CXCL10, and IL16) were analyzed by RT-qPCR. B The secretion of CXCL10 was measured by ELISA. Data are represented as mean ± SD (n = 3). *P < 0.05

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