Fig. 6
Wnt pathway targeting by SARS-CoV-2 confirmed in human iPSC-BMELCs. A Wnt7 signaling genes (WNT7a, WNT7b, RECK, and GPR124) were analyzed by RT-qPCR after SARS-CoV-2 infection (MOI = 1) for 24 h. B Wnt inhibitory genes (NKD1, NKD2, DKK1, DKK3, DKKL1, AXIN2, APCDD1, APCDD1L, SFRP1, SFRP2, SFRP4, and SFRP5) were analyzed by RT-qPCR after 24 h of SARS-CoV-2 infection (MOI = 1). C Canonical Wnt/β-catenin target genes (CCND1, FGF20, FN1, MCT1, MYC, and WISP1) were analyzed by RT-qPCR after 24 h of SARS-CoV-2 infection (MOI = 1). Data are represented as mean ± SD (n = 3). *P < 0.05