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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: SARS-CoV-2 causes dysfunction in human iPSC-derived brain microvascular endothelial cells potentially by modulating the Wnt signaling pathway

Fig. 2

SARS-CoV-2 receptor for infection examined in human iPSC-BMELCs. A Expression of SARS-CoV-2 receptor candidates was determined by RT-qPCR. B Cells were treated with ACE2 Ab (20 μg/mL), Meplazumab (20 μg/mL), Bemcentinib (1 μM), or EG00229 (100 μM) 1 h before SARS-CoV-2 infection (MOI = 1). The intracellular viral copy number was determined by RT-qPCR. Normalized value of SARS-CoV-2 RNA copies was indicated against vehicle control as 100%. Data are represented as mean ± SD (n = 3)

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