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Table 6 Effect Size Estimates for Normalized Distance to Platform in Probe Trials

From: Cognitive decline, Aβ pathology, and blood–brain barrier function in aged 5xFAD mice

Effect

Estimatea

χ2 (df)

p

Genotype (5xFAD)

− 0.115 ± 0.033

10.854 (1)

 < 0.001

Test duration

0.106 ± 0.033

58.906 (1)

 < 0.001

Age

− 0.061 ± 0.013

10.410 (1)

0.001

Test day

− 0.103 ± 0.013

21.351 (1)

 < 0.001

Genotype × Test day

0.111 ± 0.034

4.468 (1)

0.035

Genotype × Test duration

0.028 ± 0.013

15.349 (1)

 < 0.001

  1. Estimates are reported with corresponding p values, chi-squared values, and degrees of freedom
  2. aCalculated as log odds ratio ± standard error
  3. bCalculated on a log link ± standard error. Relevant effect sizes with p < 0.05 are discussed in the results section and shown in bold text here
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Fluids and Barriers of the CNS

ISSN: 2045-8118