Cognitive decline, Aβ pathology, and blood–brain barrier function in aged 5xFAD mice

Table 5 Effect Size Estimates for Percent Time Spent in Target Quadrant in Probe Trials

Effect	Estimate^a	χ² (df)	p	R²
Genotype (5xFAD)	− 0.377 ± 0.077	23.974 (1)	< 0.001	0.253
Age	− 0.285 ± 0.076	14.059 (1)	< 0.001	0.109
Test Duration	0.315 ± 0.059	28.289 (1)	< 0.001	0.087
Test Day	0.260 ± 0.049	28.362 (1)	< 0.001	< 0.001
Genotype × Test Duration	0.100 ± 0.054	20.946 (1)	< 0.001	0.051
Age × Test Duration	0.256 ± 0.056	3.447 (1)	0.063	0.011
Genotype × Test Day	− 0.097 ± 0.048	4.020 (1)	0.045	< 0.001

Effect size estimates for percent time spent in target quadrant with corresponding p values, chi-squared values, R² values, and degrees of freedom
^aCalculated as log odds ratio ± standard error
^bCalculated on a log link ± standard error. Relevant effect sizes with p < 0.05 are discussed in the results section and shown in bold text here

ISSN: 2045-8118