Cognitive decline, Aβ pathology, and blood–brain barrier function in aged 5xFAD mice

Table 4 Effect Size Estimates for Search Strategy Preferences in MWM test

Effect	Estimate^a	χ² (df)	p
Age	0.075 ± 0.061	0.000 (1)	1.000
Genotype (5xFAD)	0.297 ± 0.065	0.000 (1)	1.000
Test Day	− 0.744 ± 0.070	193.095 (1)	< 0.001
Test Phase (Cued)	− 0.728 ± 0.087	150.088 (1)	< 0.001
Age × Genotype	0.217 ± 0.060	9.109 (1)	0.003
Age × Test Phase	− 0.098 ± 0.032	20.594 (1)	< 0.001
Genotype × Test Day	0.103 ± 0.040	7.654 (1)	0.006
Genotype × Test Phase	0.136 ± 0.050	12.304 (1)	< 0.001
Test Phase × Test Day	− 0.362 ± 0.069	47.111 (1)	< 0.001
Age × Genotype × Test Phase	− 0.054 ± 0.032	6.140 (1)	0.013
Age × Genotype × Strategy Efficiency	0.036 ± 0.103	59.461 (8)	< 0.001

Effect size estimates for search strategy preferences with corresponding p values, chi-squared values, and degrees of freedom. Positive values indicated that the effect was associated with higher structured strategies
^aCalculated as the log of odds ratio ± standard error

ISSN: 2045-8118