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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Cognitive decline, Aβ pathology, and blood–brain barrier function in aged 5xFAD mice

Fig. 3

Search Strategy Assessment in MWM Testing. Search strategies were assigned to trials as described herein. A Spatial direct strategies imply that mice found the platform directly. B Spatial indirect strategies imply that mice find the platform within one loop. C Focal correct strategies involve a focused search adjacent to the platform. D An incorrect focal strategy implies a focused search in a small portion of the pool that does not contain the platform. E Scanning implies a platform search across the pool. F Random strategies imply a non-focused search in the entire pool. G Chaining involves a repetitive platform search inside the thigmotaxis zone, i.e., 15 cm from the rim of the pool. H Peripheral looping involves a platform search within the thigmotaxis zone. I Circling strategies involve movements in tight circles with directionality

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