Fig. 2From: Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood–brain barrierZebrafish ABCG2 homologs confer resistance to cytotoxic ABCG2 substrates. HEK-293 cells stably expressing empty vector, ABCG2 or Abcg2a-d were treated with known cytotoxic ABCG2 substrates for 3 days. GI50 and relative resistance values are summarized in Additional file 5: Table S1Back to article page