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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Fasting upregulates the monocarboxylate transporter MCT1 at the rat blood-brain barrier through PPAR δ activation

Fig. 4

Effect of fasting on PPAR isoforms and target genes in CECs and whole cortex. Rats were fed ad libitum (AL) or fasted for one day (F1), two days (F2), or three days (F3). (a) Mean counts and Log2 fold change (LFC) relative to AL rats for selected transcripts (ns: not significantly different from AL, NA: LFC cannot be calculated because of too low expression). These figures were extracted from the whole RNA-Seq dataset presented in Suppl. Table S1. (b) Measurement of the abundance of Ppara, Ppard and Pparg transcripts in MACS-isolated rat CECs and whole cortex by qRT-PCR. Mean ± SD. One-way ANOVA with Holm-Sidak’s multiple comparisons test

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Fluids and Barriers of the CNS

ISSN: 2045-8118