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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: The proteome of the blood–brain barrier in rat and mouse: highly specific identification of proteins on the luminal surface of brain microvessels by in vivo glycocapture

Fig. 3

Comparison of in vivo glycocapture to a whole brain lysate glycocapture. A Number of proteins identified by in vivo glycocapture and by brain lysate glycocapture in rat and mouse. B Distribution of the vessel enrichment scores for all proteins identified proteins by in vivo glycocapture with the highest scoring and lowest scoring proteins indicated. C Gene ontology and Reactome pathway enrichment analysis for the 194 in vivo glycocapture proteins with a vessel enrichment score > 1000. All listed categories had at least a twofold enrichment value with an FDR p-value < 0.05 when using a reference of the 1367 proteins identified in all glycocapture experiments, including both in vivo glycocapture and brain lysate glycocapture

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Fluids and Barriers of the CNS

ISSN: 2045-8118