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Table 2 Patient characteristics at baseline, comparing those who displayed at least one FoG episode with those who did not, pre-surgery

From: Freezing of gait in idiopathic normal pressure hydrocephalus

 

Total sample

(n = 139)

Patients without FoG

(n = 117)

Patients with FoG

(n = 22)

p-value

Age

75 (71–79)

75 (71–78)

78 (76–79)

0.029a

Female sex

48 (35%)

41 (35%)

7 (32%)

0.77b

Smoker

16 (12%)

(n = 136)

14 (12%)

(n = 114)

2 (9%)

1.0d

Diabetes

52 (37%)

40 (34%)

12 (55%)

0.07b

Parkinsonian syndrome

7 (5.0%)

6 (5.1%)

1 (4.5%)

1.0d

MMSE*

25 (21–27)

(n = 138)

25 (22–27)

(n = 116)

21 (17–26)

0.031c

Disease duration (years)

2 (1–3)

(n = 131)

2 (1–3)

(n = 109)

4 (2–5)

< 0.001c

Maximum walking speed (m/s)

0.83 (0.60–1.10)

(n = 137)

0.87 (0.68–1.10)

(n = 116)

0.57 (0.45–0.73)

(n = 21)

< 0.001a

Tinetti POMA balance score*

11 (8–13)

11 (9–14)

7 (4–10)

< 0.001c

Tinetti POMA gait score*

8 (5–10)

8 (6–10)

3 (1–5)

< 0.001c

Tinetti POMA test total score*

18.0 (13.0–22.0)

20.0 (15.0–23.0)

9.5 (6.0–14.0)

< 0.001c

TUG Time (seconds)

18.1 (14.3–25.1)

(n = 74)

18.1 (14.3–24.0)

(n = 69)

27.5 (15.3–28.0)

(n = 5)

0.489c

Shunt surgery

91 (66%)

76 (65%)

15 (68%)

0.77b

Median follow-up-time (days)

168 (112–247)

(n = 91)

162 (110–244)

(n = 76)

215 (122–265)

(n = 15)

0.33c

Fazekas grade

2 (2–3)

(n = 123)

2 (2–3)

(n = 106)

2 (1–2)

(n = 17)

0.243c

Framingham Risk Score

30.7 (20.2–44.5)

(n = 132)

29.6 (20.0-43.2)

(n = 110)

36.5 (21.2–48.9)

0.323c

  1. Values indicate median (interquartile range) or no. (%). P-value representing significance in the difference between patients with and without FoG for each variable. Sample sizes are displayed in the top row unless stated otherwise in a specific cell. Statistically, significant comparisons are bold-typed
  2. Abbreviations: * Higher is better, a= Independent two-tailed t-test, b= Person chi-square, c= Independent-samples Mann-Whitney U test, d= Fisher’s exact test, FoG = Freezing of gait, n = sample size, no.=number of patients, TUG = Time up and go, SD = Standard deviation, POMA = Performance Oriented Mobility Assessment