Fig. 7

Pericyte coverage but not astrocyte polarity is diminished in α5-TPKO mice. A Representative images of PDGFRβ (green) and Podocalyxin (red) staining in the cortex of 4 ∼ 6-month-old control and α5-TPKO mice (both sexes). Scale bar: 25 μm. B-G Quantifications of pericyte coverage (B, D, and F) and contact (C, E, and G) in the cortex (B and C), hippocampus (D and E), and striatum (F and G) of control and α5-TPKO mice. *p = 0.0159 and **p = 0.0079, Mann-Whitney U test. n = 5 mice. Data were shown as mean ± SD. H Representative images of AQP-4 (green) and Podocalyxin (red) staining in the cortex of 4 ∼ 6-month-old control and α5-TPKO mice (both sexes). Scale bar: 50 μm. I-N Quantifications of AQP-4 coverage (I, K, and M) and contact (J, L, and N) in the cortex (I and J), hippocampus (K and L), and striatum (M and N) of control and α5-TPKO mice. non-significant, Mann-Whitney U test. n = 5 mice. Data were shown as mean ± SD