Fig. 3
From: Endothelial and mural laminin-α5 contributes to neurovascular integrity maintenance
α5-TPKO mice show increased neurovascular permeability. A Representative images of Sulfo-NHS-Biotin (green) and Podocalyxin (red) staining in the cortex of 4 ∼ 6-month-old control and α5-TPKO mice (both sexes). Scale bar: 50 μm. B Quantification of Sulfo-NHS-Biotin fluorescent intensity in control and α5-TPKO brains. **p = 0.0079, Mann-Whitney U test. n = 5 mice. Data were shown as mean ± SD. C Representative images of Hemoglobin (green) and Podocalyxin (red) staining in the cortex of 4 ∼ 6-month-old control and α5-TPKO mice (both sexes). Scale bar: 50 μm. D Quantification of Hemoglobin fluorescent intensity in control and α5-TPKO brains. **p = 0.0079, Mann-Whitney U test. n = 5 mice. Data were shown as mean ± SD