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Table 2 Quantitative results of the breathing effects on four parameters of CSF at extracranial (C2-C3) and intracranial (aqueduct) planes

From: Validating the accuracy of real-time phase-contrast MRI and quantifying the effects of free breathing on cerebrospinal fluid dynamics

 

C2-C3 (n = 25)

 

Mean value

Δp

Δp%

Φp°

Δp% without Φp°

p value

Qnet (ml/min)

9.4 ± 5.6

20 ± 9.9

6.3 ± 3.1

33 ± 27

5.3 ± 2.8

**

Amplitude (ml/min)

338 ± 82

22 ± 9

6.8 ± 2.8

-11 ± 75

2.2 ± 3.7

**

SV (mm3)

608 ± 160

85 ± 56

14 ± 7.1

-36 ± 43

8.7 ± 6.4

**

Tc (ms)

832 ± 164

49 ± 28

6.0 ± 3.4

-64 ± 51

2.5 ± 3.4

**

 

Aqueduct (n = 20)

 

Mean value

Δp

Δp%

Φp°

Δp% without Φp°

p value

Qnet (ml/min)

-0.34 ± 0.93

2.8 ± 1.7

11 ± 6.8

58 ± 36

6.5 ± 5.7

**

Amplitude (ml/min)

26 ± 12

2.9 ± 1.8

11 ± 4.9

-80 ± 82

-1.6 ± 8.8

0.36

SV (mm3)

55 ± 34

9.0 ± 7.5

15 ± 5

-42 ± 60

1.9 ± 9.4

0.43

Tc (ms)

837 ± 154

51 ± 32

5.8 ± 3.4

-40 ± 47

3.4 ± 3.2

**

  1. Δp indicates the difference between the inspiratory and expiratory phases of the corresponding parameter-p, Δp% is the percentage expression. Δp% without Φp° indicates the Δp% without taking into account the phase shift (Φp° = 0). The statistical significance (p-value) of Δp% without Φp° compared to zero is tested with t-test (* = p < 0.05; ** = p < 0.01)