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Table 1 Demographic and clinical characteristics of the two study groups before and after stabilized inverse probability of treatment weighting (IPTW)

From: Cerebrospinal fluid shunt surgery reduces the risk of developing dementia and Alzheimer’s disease in patients with idiopathic normal pressure hydrocephalus: a nationwide population-based propensity-weighted cohort study

 

Before IPTW

After IPTW

Shunt surgery (n = 376)

No-shunt surgery (n = 1677)

SMD

Shunt surgery (n = 375.0)

No-shunt surgery(n = 1677.4)

SMD

Age (year)

 Average

73.69 ± 7.18

76.54 ± 7.62

0.385

75.53 ± 7.41

76.14 ± 7.61

0.081

 60–69

108 (28.7%)

343 (20.5%)

0.193

81 (21.6%)

367 (21.9%)

0.008

 70–79

185 (49.2%)

704 (42%)

0.145

166 (44.3%)

728 (43.4%)

0.018

 80 + 

83 (22.1%)

630 (37.6%)

0.344

128 (34.1%)

582 (34.7%)

0.012

Sex

 Male

215 (57.2%)

953 (56.8%)

0.007

210 (56.1%)

954 (56.9%)

0.016

 Female

161 (42.8%)

724 (43.2%)

0.007

165 (43.9%)

723 (43.1%)

0.016

Monthly income (NTD)

  ≤ 15839

59 (15.7%)

405 (24.2%)

0.213

83 (22.2%)

379 (22.6%)

0.010

 15840–24999

222 (59%)

906 (54%)

0.101

209 (55.6%)

922 (55%)

0.013

 25000–39999

53 (14.1%)

207 (12.3%)

0.052

47 (12.6%)

213 (12.7%)

0.004

  ≥ 40000

42 (11.2%)

159 (9.5%)

0.056

36 (9.6%)

164 (9.8%)

0.004

Incidence year

 2001–2006

114 (30.3%)

535 (31.9%)

0.034

119 (31.7%)

531 (31.6%)

0.002

 2007–2012

115 (30.6%)

606 (36.1%)

0.118

133 (35.5%)

588 (35.1%)

0.009

 2013–2018

147 (39.1%)

536 (32%)

0.150

123 (32.8%)

558 (33.3%)

0.011

Comorbidity

 CCI score

2.06 ± 1.8

1.78 ± 1.8

0.155

1.85 ± 1.69

1.83 ± 1.80

0.011

 Coronary artery disease

54 (14.4%)

309 (18.4%)

0.110

66 (17.6%)

296 (17.7%)

0.002

 Chronic kidney disease

31 (8.2%)

136 (8.1%)

0.005

29 (7.7%)

137 (8.2%)

0.017

 Hypertension

261 (69.4%)

1027 (61.2%)

0.172

231 (61.6%)

1052 (62.7%)

0.024

 Type II diabetes mellitus

105 (27.9%)

499 (29.8%)

0.040

109 (29.1%)

493 (29.4%)

0.007

  1. Continuous variables are presented as mean ± standard deviation. Categorical variables are presented as frequencies and percentages. NTD, new Taiwan dollar. CCI, Charlson comorbidity index. A standardized mean difference (SMD) ≤ 0.1 indicates a negligible difference between the two study groups. SMD > 0.1 is indicated by bold font