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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: Oxygen glucose deprivation-pretreated astrocyte-derived exosomes attenuates intracerebral hemorrhage (ICH)-induced BBB disruption through miR-27a-3p /ARHGAP25/Wnt/β-catenin axis

Fig. 6

ARHGAP25 was a target gene of miR-27a-3p A. Venn diagram analysis of the predicted downstream target genes of miR-27a-3p by miRanda, PITA and RNAhybrid databases. B. The putative miR-27a-3p binding sites in ARHGAP25 C-D. Western blot and quantitative analysis of ARHGAP25. E. Luciferase reporter assay to evaluate the interaction ability between miR-27a-3p 3ʹ—UTR and ARHGAP25. **p < 0.01 versus indicated group; *p < 0.05 versus indicated group. All data were expressed as mean ± SEM of at least 3 independent experiments

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Fluids and Barriers of the CNS

ISSN: 2045-8118