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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Oxygen glucose deprivation-pretreated astrocyte-derived exosomes attenuates intracerebral hemorrhage (ICH)-induced BBB disruption through miR-27a-3p /ARHGAP25/Wnt/β-catenin axis

Fig. 4

miRNA expression signature profiling in OGD-ADEVs A. miRNA volcano plot. Red point in the plot represents differentially upregulated miRNAs, and green point represents downregulated miRNAs, with statistical significance (fold change > 2.0 or < − 2.0; P < 0.05) C–D. The bubble map of GO enrichment and KEGG pathway analysis of miRNA target genes. D. A heat map of the first 20 significantly differentially expressed miRNAs. E. Expression of miR-27a-3p in N-ADEVs and OGD-ADEVs evaluated by qRT-PCR

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Fluids and Barriers of the CNS

ISSN: 2045-8118