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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Oxygen glucose deprivation-pretreated astrocyte-derived exosomes attenuates intracerebral hemorrhage (ICH)-induced BBB disruption through miR-27a-3p /ARHGAP25/Wnt/β-catenin axis

Fig. 2

ADEVs protected against barrier hyperpermeability and TJPs disruption in bEnd.3 cells after hemin treatment A. Determination of TEER to evaluate the barrier integrity of monolayer bEnd.3 cells. B. Western blot analysis of tight junction protein markers (occludin, Claudin-5, and ZO-1) in bEnd.3 cells. C. Immunofluorescence staining for ZO-1 in bEnd.3 cells D–E. Quantification of the relative protein expression levels of occludin, Claudin-5, and ZO-1. **p < 0.01 versus indicated group; *p < 0.05 versus indicated group. All data were expressed as mean ± SEM of at least 3 independent experiments

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Fluids and Barriers of the CNS

ISSN: 2045-8118