Fig. 1

Cerebral blood and intracranial pressures during BPL. A, C, Blood pressure (BP) and intracranial pressure (ICP) during BPL with nicardipine (Ncrd) on separate groups of mice. Multiple unpaired t-tests with Welch’s corrections. B, D, Comparisons of selected timepoints in control and BPL groups. Ordinary two-way ANOVA with Šidák’s multiple comparisons. A–D, *P < 0.05, ns = non-significant. A, B, n = 4–9 mice per group. C, D, n = 5–6 mice per group. Filled and open circles in B and D represent individual mice at different timepoints taken from the graphs A and C, respectively