Fig. 4

Albumin perfusate impacts microdialysate catheter clustering and a subset of metabolites. A Pearson correlation of the 162 normalized metabolites present in at least 90% catheters revealed clustering of microdialysates in which albumin was utilized as a perfusate. Batch and perfusate types are annotated. B A heat map was generated for the top 25 differentially abundant metabolites between the albumin versus dextran-containing microdialysates (both in batch 2) and these metabolites’ normalized peak areas in batch 2 patients; only the second batch is shown (see Additional file 1: Fig. S3 for full data across the 3 batches)