Fig. 3
From: A metabolomics study in aqueous humor discloses altered arginine metabolism in Parkinson’s disease
Multivariant metabolite analyses. (A) Principal component analysis diagram. The space and data for controls are in yellow and the space and data for PD individuals are in blue. Principal component (PC) 1, PC2, and PC3 explain, respectively, the 63.8%, the 12.0%, and the 9.0% of the between-group variance. (B) Dendrogram and heatmap. It shows the similarity index between the differentially concentrated metabolites in PD patients. The similarity index was obtained using Pearson’s correlation coefficient (the darker the blue, the higher the similarity index). Compounds displaying a similarity index greater than 0.5 are in blue the darker the red, the lower the similarity index). (C) Linear discrimination analysis. Probability of being classified as a control using the LDF1 function with cross-validation. The colors of the bars indicate the classification result (gold: control (C); blue: PD patient (P)). The overall performance of the cross-validated function is 93.75%