Fig. 2
From: SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation
Sspo-deficiency leads to reduced ventricle volume at 6 weeks. A Schematic depicting brain regions captured by MRI and manual ventricle segmentation. B Representative sequential MR images of Sspo+/+ and Sspo−/− brains, showing reduced ventricle (white) sizes in Sspo−/− mice. C 3D rendering of lateral and third ventricles from Sspo+/+ and Sspo−/− mice. D Quantification of lateral and third ventricle volumes. Male and female mice were analyzed and plotted together but marked separately. * p = 0.0193, Welch’s t-test. Data presented as mean ± S.D