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Table 1 Biochemistry and cytokines concentration in rat plasma

From: miRNA-ome plasma analysis unveils changes in blood–brain barrier integrity associated with acute liver failure in rats

 

Control

OA

TAA

Ammonia (µmol/L)

62 ± 7

93 ± 11**

139 ± 11***

AST (units/L)

163 ± 17

175 ± 47

1958 ± 851***

ALT (units/L)

64 ± 6

70 ± 10

442 ± 154***

GGTP (units/L)

1.7 ± 0.3

1.9 ± 0.7

2.1 ± 0.4

TNFα (pg/mL)

0.039 ± 0.103

0.009 ± 0.024

5.435 ± 10.150

IL-1α (pg/mL)

4.970 ± 7.678

6.034 ± 4.177

59.648 ± 42.246

IL-1β (pg/mL)

n.d.

0.427 ± 1.131***

1.874 ± 6.215***

IL-6 (pg/mL)

95 ± 106

n.d.

10,022 ± 1355***

IL-10 (pg/mL)

n.d.

n.d.

1592 ± 3313***

  1. Results are mean ± SD. n = 6; **p < 0.01, ***p < 0.001 vs. control