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Fig. 7 | Fluids and Barriers of the CNS

Fig. 7

From: Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency

Fig. 7

Evaluation of the blood vessel distribution in the mice cerebral cortex. A Representative microphotographs of mouse blood vessels stained with Tomato-Lectin (red) in the motor cortex of WT and Mct8/Dio2KO at P90 and P180. B Quantification of Tomato-Lectin staining showing vessel covered area in the motor cortex of WT and Mct8/Dio2KO mice at P90 and P180. C Representative microphotographs of mouse blood vessels stained with Tomato-Lectin (red) in the somatosensory cortex of WT and Mct8/Dio2KO at P90 and P180. D Quantification of Tomato-Lectin staining showing vessel covered area in the somatosensory cortex of WT and Mct8/Dio2KO mice at P90 and P180. Scale bar: 100 µm for all panels. n = 4 for each experimental group of animals. Abbreviations: FC = fold change. Data are expressed as bar plots with individual values, mean ± SD. P-values *p < 0.05 were determined by unpaired Student’s t-test

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