Fig. 2

Illustration of the physiological adaptation of a number of transporters on brain endothelial cells with the transition from the use of the ketone bodies during lactation to that of mostly glucose after weaning. The endothelial cells adapt the number of monocarboxylate transporters (MCT in Blue) in function of the need of the energy substrate, with higher number of MCT during lactation to facilitate the ketone bodies to fuel the brain than in the adulthood with the use of glucose from the general blood circulation. It is similar to a country facilitating product importation in function of its needs (Fig. 3)