Fig. 1
From: Methylglyoxal, a highly reactive dicarbonyl compound, as a threat for blood brain barrier integrity
Effects of methylglyoxal (MGO) on the different cell types of the blood-brain barrier (BBB). Schematic representation of the BBB including vascular smooth muscle cells (VSMCs), pericytes, endothelial cells, astrocytes, and microglial cells. The boxes contain the effect MGO exposure has on the respective cell type including the cited literature. Abbreviations: reactive oxygen species (ROS); inducible nitric oxide synthase (iNOS); platelet-derived growth factor receptor β (PDGFRβ); receptor of advanced glycation end products (RAGE)