Table 3 Peroperative ventricular CSF biomarker concentrations of subsequently unimproved and improved patients
Unimproved (n = 38) Median (IQR) (ng/L) | Improved (n = 81) Median (IQR) (ng/L) | P ‡ | |
|---|---|---|---|
Aβ40 | 3900 (2486–5314) | 3840 (2210–5470) | 0.752 |
Aβ42 | 316 (197–436) | 312 (197–435) | 0.462 |
Aβ42/40 | 0.08 (0.065–0.095) | 0.09 (0.075–0.105) | 0.080 |
APPα | 79 (43–115) | 68 (37–100) | 0.433 |
APPβ | 218 (134–303) | 203 (128–279) | 0.745 |
P-tau | 45 (28–62) | 50 (30–70) | 0.162 |
T-tau | 523 (298–749) | 637 (294–981) | 0.059 |
NfL | 870 (601–1139) | 820 (530–1110) | 0.470 |
GFAP | 960 (566–1354) | 900 (505–1295) | 0.650 |
YKL40 | 99 (74–125) | 99 (66–133) | 0.871 |
MCP1 | 458 (380–536) | 437 (350–524) | 0.535 |
Neurogranin | 330 (205–456) | 365 (186–544) | 0.046 |
GAP43 | 2323 (1507–3139) | 2167 (1365–2970) | 0.257 |