Table 2 Biomarker levels in peroperative ventricular CSF of iNPH patients
N | Mean (± SD) (ng/L) | Median (IQR) (min–max) (ng/L) | |
|---|---|---|---|
Aβ40 | 119 | 4256 (± 2151) | 3880 (2620–5570) (914–11,740) |
Aβ42 | 119 | 346 (± 189) | 314 (193–428) (68–988) |
Aβ42/40 | 119 | 0.08 (± 0.02) | 0.09 (0.07–0.1) (0.04–0.12) |
APPα | 119 | 90 (± 58) | 73 (52–123) (18–321) |
APPβ | 119 | 228 (± 122) | 203 (144–295) (31–673) |
P-tau | 119 | 63 (± 54) | 49 (34–74) (14–377) |
T-tau | 119 | 834 (± 891) | 617 (373–1030) (75–7110) |
NfL | 118 | 1102 (± 754) | 845 (655–1243) (160–4980) |
GFAP | 116 | 1297 (± 1208) | 935 (64–1420) (200–6660) |
YKL40 | 117 | 107 (± 48) | 99 (71–135) (34–307) |
MCP1 | 117 | 479 (± 166) | 440 (364–543) (151–1140) |
Neurogranin | 117 | 434 (± 279) | 351 (245–566) (74–1700) |
GAP43 | 115 | 2625 (± 1556) | 2233 (1532–3107) (540–8463) |