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Table 1 Demographic data of 119 iNPH patients

From: Association between ventricular CSF biomarkers and outcome after shunt surgery in idiopathic normal pressure hydrocephalus

 

All patients

Unimproved

Improved

P

n = 119

n = 38 (32%)

n = 81 (68%)

Duration of symptoms (months)

36 (21–48)

36 (23–49)

30 (10–41)

0.995 *

Time from diagnosis to surgery (days)

106 ± 52

108 ± 9

105 ± 6

0.817§

Age (years)

74 ± 7

76 ± 7

74 ± 7

0.930§

Sex (men)

n = 76 (64%)

n = 27 (71%)

n = 49 (60%)

0.310 ‡

Body mass index

27 ± 4

27 ± 5

27 ± 3

0.224§

Vascular risk factors: heart disease, hypertension, or Diabetes mellitus (yes)

n = 84 (71%)

n = 28 (74%)

n = 56 (69%)

0.671 ‡

Heart disease (yes)

n = 35 (29%)

n = 13 (34%)

n = 22 (27%)

0.282‡

Hypertension (yes)

n = 70 (59%)

n = 23 (61%)

n = 47 (58%)

0.478‡

Diabetes mellitus (yes)

n = 36 (30%)

n = 11 (29%)

n = 25 (31%)

0.505‡

MMSE

26 (24–28)

26 (21–31)

26 (22–30)

0.630 §

Preoperative iNPH scale score

54 ± 17

54 ± 17

53 ± 17

0.759§

Postoperative iNPH scale score

66 ± 18

56 ± 17

70 ± 17

 < 0.001§

Delta iNPH scale score

12 ± 11

2 ± 2

17 ± 9

 < 0.001§

  1. Values are given as mean (± SD) or median (IQR), MMSE = mini mental state examination. A delta iNPH scale score < 5 defines unimproved patients, while a delta iNPH scale score of ≥ 5 indicates improved patients. P-values represent comparisons across groups of unimproved and improved patients
  2. *Mann Whitney U test
  3. §Student’s t-test
  4. Chi2 test.