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Table 2 Values are presented as mean ± standard error; n.s.:no statistical significance, and *p < 0.05, n = 5

From: In vitro investigation of the effect of proinflammatory cytokines on mouse choroid plexus membrane transporters Ncbe and NKCC1

TEER values (Ω*cm2)

TNFα

 

Treatment

Control

1 pg/mL

1 ng/mL

100 ng/mL

24 h

Start

138 ± 8

149 ± 8

154 ± 11

157 ± 8

 

End

122 ± 8 n.s.

140 ± 11 n.s.

132 ± 6 n.s.

132 ± 7*

48 h

Start

217 ± 12

195 ± 14

212 ± 20

230 ± 22

 

End

233 ± 22 n.s.

218 ± 3 n.s.

229 ± 37 n.s.

206 ± 10 n.s.

IL-1β

 

Treatment

Control

1 pg/mL

1 ng/mL

100 ng/mL

24 h

Start

143 ± 13

140 ± 14

144 ± 12

165 ± 13

 

End

145 ± 19 n.s.

157 ± 18 n.s.

131 ± 19 n.s.

132 ± 15*

48 h

Start

143 ± 9

136 ± 9

135 ± 7

150 ± 7

 

End

142 ± 19 n.s.

136 ± 18 n.s.

145 ± 13 n.s.

165 ± 18 n.s.

IL-6

 

Treatment

Control

1 pg/ml

1 ng/ml

100 ng/ml

24 h

Start

132 ± 4

127 ± 9

137 ± 4

143 ± 7

 

End

141 ± 7 n.s.

138 ± 5 n.s.

139 ± 12 n.s.

147 ± 6 n.s.

48 h

Start

174 ± 18

195 ± 19

164 ± 15

178 ± 29

 

End

190 ± 15 n.s.

204 ± 16 n.s.

193 ± 12 n.s.

190 ± 27 n.s.

100 ng/mL prolonged treatment

 

Treatment

Control

TNFα

IL-1β

IL-6

72 h

Start

170 ± 30

177 ± 54

152 ± 30

221 ± 20

 

End

147 ± 27 n.s.

148 ± 29 n.s.

159 ± 21 n.s.

166 ± 14*