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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Levels of inflammatory cytokines MCP-1, CCL4, and PD-L1 in CSF differentiate idiopathic normal pressure hydrocephalus from neurodegenerative diseases

Fig. 4

To investigate if a model of the four proteins MCP-1, CCL4, PD-L1 and CCL11 could predict diagnosis of iNPH vs AD, MCI/AD, MCI or FTD, a PLS-DA multivariate model was built. A. PLS-DA score plot. B. Loading plot with the four proteins. C. The VIP (variable of importance) values illustrates the predictive importance of a variable in the model. The red dots represent the VIP for the full model (based on all data). The boxplots represent the VIP for the cross validated models

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