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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Levels of inflammatory cytokines MCP-1, CCL4, and PD-L1 in CSF differentiate idiopathic normal pressure hydrocephalus from neurodegenerative diseases

Fig. 1

Principal component analysis (PCA) based on levels of 56 cerebrospinal fluid proteins. The score plot is colored according to (A) patient groups, (B) plate number (three plates were used) and (C) age. All included data is reduced into two dimensions. PC1 is the combination with the largest possible explained variation, PC2 is the second most important direction and orthogonal from PC1. Loading plot illustrated in (D) with proteins with higher levels in iNPH-patients in the bottom and lower levels in the top. iNPH idiopathic normal pressure hydrocephalus, AD Alzheimer’s disease, MCI/AD mild cognitive impairment due to Alzheimer’s disease, MCI mild cognitive impairment, FTD frontotemporal dementia and C controls

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Fluids and Barriers of the CNS

ISSN: 2045-8118