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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: BBB opening by low pulsed electric fields, depicted by delayed-contrast MRI, enables efficient delivery of therapeutic doxorubicin doses into mice brains

Fig. 6

Representative brain slices showing BBBo for the combined L-PEFs + Doxo group and the Doxo only group immediately post treatment. A representative contrast-enhanced T1-MRI slice depicting the enhancing tumor (arrow) is shown on the left, and 2 slices showing pixels included in the area over the threshold (AOT), representing BBBo near the tumor and in further cortical areas, are shown on the right. (A) Combined L-PEFs + Doxo group (N = 5). (B) Doxo only group (N = 5)

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