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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: BBB opening by low pulsed electric fields, depicted by delayed-contrast MRI, enables efficient delivery of therapeutic doxorubicin doses into mice brains

Fig. 2

Doxo toxicity towards Gl261 and U87 glioma cells. Cells were seeded in a 96 wells plate and confluence was automatically measured in real-time using Incucyte. Four and single experiments for Gl261 (A) and U87 (B), respectively, with n = 6 wells/concentration in each and 12 wells for control cells (vehicle) in each experiment. Shown are averaged percent confluence at day 5. Calculated IC50 are 7.1 ± 2.8 nM and 86.6 ± 10.0 nM (Average ± SEM) for Gl261 and U87, respectively (non-linear fit, GraphPad Prism7)

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