Fig. 1From: Proteomic alterations in the brain and blood–brain barrier during brain Aβ accumulation in an APP knock-in mouse model of Alzheimer’s diseaseAlterations in brain Aβ accumulation and protein levels in APP-KI mice. A Accumulation of Aβ (82E1) in the brains of 2-, 5-, and 12-month-old WT and APP-KI mice. Scale bar: 200 μm. B Protein levels in brain homogenates from 2-, 5-, and 12-month-old WT and APP-KI mice. Protein levels were normalized to brain weight and the relative ratio to WT at 2 months. Bars represent mean ± SD values (n = 3–5). Plotted points represent individual valuesBack to article page