Fig. 2
Representative images. QSM (A) and corresponding kw (B) and kw/CBF (C) maps obtained from eligible participants— a 6-month-old boy, 24-month-old girl, 40-month-old boy, and 93-month-old boy are displayed. In QSM, the interfaces between the deep gray-matter nuclei and surrounding white matter were only slightly visible at 6 months of age. With increasing age, these boundaries were gradually distinguishable, with the highest susceptibility value in the globus pallidus. In contrast, the differences in the kw and kw/CBF maps were indiscernible except that the kw/CBF map at 6 months broadly showed high kw/CBF values, especially in the basal ganglia. BBB = blood-brain barrier, CBF = cerebral blood flow, QSM = quantitative susceptibility, R = right