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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Inhibition of serum- and glucocorticoid-induced kinase 1 ameliorates hydrocephalus in preclinical models

Fig. 4

Trpv4 and Sgk1mRNA expression in rat choroid plexus. (A) Agarose gel of RT-PCR products showing the presence of Sgk1 and Trpv4 in rat choroid plexus. B qRT-PCR analysis of normal and mutant (P394L) choroid plexus lysates with and without SI113 treatment (n = 3 biological replicates, technical triplicates) with Trpv4 and Sgk1, primers. Although there were statistically significant differences, no genes demonstrated more than two-fold changes in either direction from the normal, untreated animal. Data represented as mean ± sem in all graphs. TRPV4 = transient receptor potential vanilloid 4; Serum/glucocorticoid regulated kinase-1 = SGK1. Primer information can be found in Table 1

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Fluids and Barriers of the CNS

ISSN: 2045-8118