Influence of head-over-body and body-over-head posture on craniospinal, vascular, and abdominal pressures in an acute ovine in-vivo model

Table 1 Mean pressure changes over the six sheep from the first baseline prone position (0₁°) listed first as averaged values then as the respective relative values from 0₁

Angle (˚)		cABP (mmHg)	fABP (mmHg)	ICP (mmHg)	ITP (mmHg)	CVP (mmHg)	JVP (mmHg)	IAPcr (mmHg)	IAPcd (mmHg)	IAPds (mmHg)	IAPve (mmHg)	IVP (mmHg)
0₁	Mean Pressure	80.4 ± 16.2	75.5 ± 17.7	16.8 ± 9.7	18.2 ± 8.2	7.6 ± 4.0	5.1 ± 1.6	15.9 ± 3.2	14.9 ± 1.7	12.6 ± 0.8	10.0 ± 0.4	11.4 ± 3.2
+ 13	Δ	− 8.6 ± 5.8	− 4.6 ± 5.8	− 5.9 ± 3.3	+ 5.0 ± 3.2	+ 0.4 ± 4.3	− 1.7 ± 3.1	− 4.7 ± 3.1	+ 2.4 ± 7.4	− 6.3 ± 18.9	− 2.6 ± 6.2	+ 7.0 ± 1.9
0₂	Δ	− 2.4 ± 6.2	− 0.3 ± 2.5	+ 0.9 ± 3.7	− 1.3 ± 3.4	− 0.1 ± 1.9	+ 0.0 ± 0.6	− 3.2 ± 6.8	+ 2.4 ± 6.8	− 3.7 ± 10.5	+ 1.4 ± 4.5	+ 0.8 ± 2.1
− 13	Δ	+ 6.1 ± 8.7	+ 1.5 ± 7.3	+ 10.8 ± 5.6	− 3.4 ± 4.9	− 0.1 ± 1.6	+ 2.9 ± 1.9	+ 6.4 ± 20.6	− 0.8 ± 8.4	− 1.9 ± 22.3	− 1.3 ± 2.2	− 6.1 ± 2.9
0₃	Δ	− 1.5 ± 6.0	− 1.0 ± 5.4	+ 4.0 ± 5.2	+ 1.3 ± 3.9	− 0.1 ± 2.6	− 0.9 ± 1.9	− 1.7 ± 12.5	+ 0.4 ± 4.1	− 4.9 ± 22.8	− 2.6 ± 2.8	− 1.3 ± 2.3
r		− 0.97	− 0.87	− 0.98	0.94	0.65	− 0.95	− 0.83	0.84	− 0.73	− 0.19	0.99
P-value		.036	.014	.030	.036	.045	.047	.044	0.032	.014	.030	.031

Angle (˚)		cABP_amp (mmHg)	fABP_amp (mmHg)	ICP_amp (mmHg)	ITP_amp (mmHg)	CVP_amp (mmHg)	JVP_amp (mmHg)	IAPcr_amp (mmHg)	IAPcd_amp (mmHg)	IAPds_amp (mmHg)	IAPve_amp (mmHg)	IVP_amp (mmHg)
0₁	Mean Amplitude	18.8 ± 6.6	26.0 ± 9.6	2.6 ± 1.2	3.0 ± 1.1	3.7 ± 2.0	1.2 ± 0.8	7.7 ± 7.6	4.6 ± 3.9	11. ± 10.2	6.2 ± 7.2	1.7 ± 0.8
+ 13	Δ	− 0.7 ± 5.2	− 3.2 ± 6.1	− 0.1 ± 0.6	− 0.4 ± 1.1	+ 0.2 ± 1.7	− 0.5 ± .05	− 5.1 ± 8.0	− 1.8 ± 7.1	− 9.0 ± 10.9	− 3.6 ± 7.8	+ 0.0 ± 0.2
0₂	Δ	+ 3.0 ± 2.5	− 1.9 ± 4.7	+ 0.4 ± 0.8	− 0.5 ± 0.8	+ 1.1 ± 1.6	+ 0.2 ± 0.3	+ 0.7 ± 5.1	− 3.2 ± 6.9	− 2.8 ± 18.7	− 1.7 ± 4.9	+ 0.0 ± 0.4
− 13	Δ	+ 0.3 ± 8.2	− 1.5 ± 5.1	+ 0.9 ± 0.9	− 0.3 ± 0.7	+ 0.1 ± 1.2	+ 0.9 ± 1.3	− 6.2 ± 9.8	− 2.4 ± 7.0	− 7.9 ± 9.6	− 2.1 ± 3.8	− 0.3 ± 0.4
0₃	Δ	+ 2.1 ± 2.3	− 3.9 ± 4.8	+ 0.7 ± 1.1	+ 0.0 ± 0.8	+ 0.3 ± 1.0	+ 0.5 ± 0.8	− 4.4 ± 6.7	− 2.7 ± 6.5	− 10.5 ± 10.8	− 3.4 ± 7.1	− 0.6 ± 0.7
r		− 0.49	0.31	− 0.91	0.16	− 0.07	− 0.93	0.15	0.37	0.21	− 0.01	0.66
P-value		.292	.232	.434	.465	.488	.459	.217	.168	.025	.183	.471

(+ 13°, 0₂°, − 13°, 0₃°) for cABP: carotid arterial blood pressure; fABP: femoral arterial blood pressure; ICP: intracranial pressure; ITP: intrathecal pressure; CVP: central venous pressure; JVP: jugular venous pressure; for IAPcr: cranial intra-abdominal pressure; IAPcd: caudal intra-abdominal pressure; IAPds: dorsal intra-abdominal pressure; IAPve: ventral intra-abdominal pressure; and IVP: intravesical pressure as well as mean pulse pressures for cABP_amp: carotid arterial blood pressure amplitude; fABP_amp: femoral arterial blood pressure amplitude; ICP_amp: intracranial pressure amplitude; ITP_amp: intrathecal pressure amplitude; CVP_amp: central venous pressure amplitude; JVP_amp: jugular venous pressure amplitude; IAPcr_amp: cranial intra-abdominal pressure amplitude; IAPcd_amp: caudal intra-abdominal pressure amplitude; IAPds_amp: dorsal intra-abdominal pressure amplitude; IAPve_amp: ventral intra-abdominal pressure; and IVP_amp: intravesical pressure. All values are in mmHg (mean ± SD) with Pearson correlation (r) and p-values reported. Δ denotes a change in pressure from the angle relative to the first baseline (0₁°)

ISSN: 2045-8118