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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Nocturnal increase in cerebrospinal fluid secretion as a circadian regulator of intracranial pressure

Fig. 3

Dark-light phase fluctuation in rat CSF secretion rate. A Representative time course of the dextran dilution quantified from the cisterna magna fluid collection taking place during the ventriculo-cisternal perfusion assay in mechanically-ventilated anaesthetized rats in the light phase (ZT 8 h, yellow spheres) and dark phase (ZT 20 h, grey spheres). Squares indicate the time interval employed for quantification of the CSF secretion rate illustrated in B, n = 5 of each. Data are shown as mean ± SD and statistical significance was evaluated with paired two-tailed t-test. *P < 0.05

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