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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries

Fig. 5

Network analysis of differentially expressed proteins and differential expression of extracellular matrix proteins between fractions. A Network map of 191 differentially expressed brain capillary (BC)-enriched proteins by STRING. The proteins indicated by the red circle constitute the largest network group by clustering analysis. The enlarged maps were indicated in Additional file 2: Figs. S3 and S4. B Pathways enriched in the largest network cluster containing 60 proteins indicated by the red circle in Fig. 5A. Pathways from the reactome are shown. Pathways from gene ontology and KEGG are shown in Additional file 1: Table S4. C Heatmaps of fold changes in BC-enriched extracellular matrix proteins compared between the neonatal brain capillary (nBC) and adult brain capillary (aBC) fractions. The fold is indicated by log2. FDR, false discovery rate

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Fluids and Barriers of the CNS

ISSN: 2045-8118