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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Spontaneously hypertensive rats can become hydrocephalic despite undisturbed secretion and drainage of cerebrospinal fluid

Fig. 4

The CSF secretion rate and outflow resistance is not elevated in SHRs. a Representative time course traces of the fluorescence ratio of dextran (outflow/inflow) during ventriculo-cisternal perfusion of one WKY rat and one SHR. Squared insert indicates the region used for quantification of CSF secretion rates. b CSF secretion rate in WKY rats (n = 6) and SHRs (n = 6) quantified from the fluorescence ratio of dextran. c Representative ICP traces of one WKY rat and one SHR undergoing measurements of CSF outflow resistance by infusion of aCSF at rates indicated in the figure. e CSF outflow resistance in WKY rats (n = 6) and SHRs (n = 6). Error bars represent standard deviation and statistical significance was tested with an unpaired two-tailed t-test. NS = not significant

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Fluids and Barriers of the CNS

ISSN: 2045-8118