Fig. 3From: Spontaneously hypertensive rats can become hydrocephalic despite undisturbed secretion and drainage of cerebrospinal fluidChoroid plexus NKCC1 transport activity is unaltered in SHRs. a Loss of 86Rb+ from the choroid plexus as a function of time in WKY rats (n = 5) and SHRs (n = 5) in presence or absence of 20 µM bumetanide (bum). The y-axis is the natural logarithm of the choroid plexus 86Rb+ amount left at time T (AT) divided by the initial amount at time 0 (A0). b Efflux rate constant for 86Rb+ in WKY rats (n = 5) and SHRs (n = 5) in presence or absence of 20 µM bumetanide (bum). c NKCC1-mediated 86Rb+ efflux rate constant (bumetanide-sensitive fractions) in WKY rats (n = 5) and SHRs (n = 5). Error bars represent standard deviation and statistical significance was tested with one-way ANOVA followed by Sidak’s multiple comparisons test or an unpaired-two tailed t-test. ***P < 0.001, NS = not significantBack to article page