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Table 1 Characteristics of 8 participants with AD.

From: Ultrasound-mediated blood–brain barrier opening uncovers an intracerebral perivenous fluid network in persons with Alzheimer’s disease

Subject no

Age (years)

Sex

MMSE

score

ADAS-COG score

ApoE

Brain regions treated by FUS

1

68

M

22

19

ε3/ε3

Medial temporal

2

54

F

19

24

ε3/ε3

Medial temporal, Parietal

3

63

M

24

17

ε3/ε4

Medial temporal, Parietal, Frontal

4

70

M

22

15

ε3/ε4

Medial temporal, Parietal, Frontal

5

76

F

25

17

ε3/ε4

Medial temporal, Parietal, Frontal

6

67

F

21

19

ε3/ε4

Medial temporal, Parietal, Frontal

7

57

M

20

19

ε3/ε3

Medial temporal, Parietal, Frontal

8

68

M

22

14

ε2/ε4

Medial temporal, Parietal, Frontal

  1. ADAS-COG Alzheimer’s disease assessment scale—cognitive subscale, ApoE apolipoprotein E MMSE mini-mental state examination