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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: Ultrasound-mediated blood–brain barrier opening uncovers an intracerebral perivenous fluid network in persons with Alzheimer’s disease

Fig. 6

Summary of post FUS MRI effects and temporal progression of CSF effusions. Schematic diagram showing MRI enhancement patterns in the acute post-treatment period. This includes a perivenous pattern and subarachnoid space pattern of contrast enhancement A. Schematic diagram showing intracerebral contrast tracer accumulation at various time points B. Plots showing individual sulcal effusion size progression (in cm) over 3 time points in two regions of 7 subjects C. Plots showing mean fold change in size of sulcal effusions (values normalized to day 0 post-FUS) in each individual, within frontal and parietal regions, respectively D–E. Maximum effusion size shown in two regions of 7 subjects F. Number of persons with and without delayed effusion clearance is summarized in G. Plots showing number of treated subjects with various susceptibility effect patterns H

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Fluids and Barriers of the CNS

ISSN: 2045-8118